ADVANCES IN VAGAL AFFERENT NEUROBIOLOGY by Bradley J. Undem

By Bradley J. Undem

Taking a accomplished technique during which all facets of the vagal afferent process are thought of, from the terminals within the visceral tissues to the neural pathways in the critical anxious approach, this broad textual content stories the advance, neurochemistry, anatomy, biophysics, pharmacology, and body structure of the vagal afferent nerves. The authors current experimental thoughts used to enquire the improvement, morphology, electrophysiology and reflex functionality of the vagal afferent nerves, and comprise cutting-edge stories of vagal afferent neurobiology via a number of the world's top specialists in those fields.

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M. , Glial growth factor restricts mammalian neural crest stem cells to a glial fate, Cell, 77, 349, 1994. fm Page 26 Monday, April 25, 2005 6:38 AM 26 Advances in Vagal Afferent Neurobiology 88. Hagedorn, L. , The Ets domain transcription factor Erm distinguishes rat satellite glia from Schwann cells and is regulated in satellite cells by neuregulin signaling, Dev. , 219, 44, 2000. 89. Leimeroth, R. , Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent progenitor cells, Dev.

Segmental organization of neural crest migration, Mech. , 105, 37, 2001. 82. , Genes, lineages and the neural crest: a speculative review, Phil. Trans. R. Soc. Lond. B, 355, 953, 2000. 83. M. , Trunk neural crest has skeletogenic potential, Curr. , 12, 767, 2002. 84. , 305, 211, 2001. 85. , 13, 276, 1997. 86. , Alternative neural crest cell fates are instructively promoted by TGFβ superfamily members, Cell, 85, 331, 1996. 87. M. , Glial growth factor restricts mammalian neural crest stem cells to a glial fate, Cell, 77, 349, 1994.

165,166,223 Numerous alterations in the neuronal phenotype, growth, regenerative capacity, and survival are evident during the life span of these neurons, from development through maturity. Knowledge of the influences of trophic factors, injury, and other epigenetic influences on visceral afferent neurons is growing but remains incomplete. Knowledge of the regulatory influences on visceral afferent neurons is essential to understanding the responses of the neurons to deprivation of target-derived factors, and the potential roles of neurotrophins in alleviating specific dysfunctions of these neurons.

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